Expression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders

Acknowledgements Funding was provided by the Wellcome Trust and Tenovus Scotland. Prof Fragoso is the recipient of a Post Doctoral Science without Borders grant from the Brazilian National Council for Scientific and Technological Development (CNPq, 37450/2012- 7). We also thank Aberdeen Proteomics for assistance with the western blots as well as the Microscopy and Histology Core Facility at the University of Aberdeen for confocal microscopy.Peer reviewedPublisher PD

Retinoic Acid Signalling in the Pineal Gland Is Conserved across Mammalian Species and Its Transcriptional Activity Is Inhibited by Melatonin

This article belongs to the Collection Functions of Nuclear Receptors Acknowledgments We thank David Hazlerigg for providing the MSM mice. qPCR was performed with the help of the Institute of Medical Sciences qPCR Core Facility at the University of Aberdeen.Peer reviewedPublisher PD

Safety Of Switching From Natalizumab Straight Into Fingolimod In A Group Of Jcv-positive Patients With Multiple Sclerosis

To assess safety of the switch between natalizumab and fingolimod without a washout period. Methods: Prospective data on 25 JCV positive patients who underwent this medication switch were collected and analyzed. Results: After a median period of nine months from the medication switch, there were no safety issues to report. The patients had good disease control and no adverse events were reported. Conclusion: Washout may not be necessary in daily practice when switching from natalizumab to fingolimod. Expertise on multiple sclerosis management, however, is essential for drug switching.74865065

Patients with multiple sclerosis do not necessarily consume more alcohol or tobacco than the general population

Peer reviewedPublisher PD